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With the summer mosquito season in full swing, Puerto Rico and a handful of counties in southern Floridaboth with rising numbers of local casesare the US hot spots of Zika activity. Travel and illness dates link Texas case to Miami The Texas patient had recently returned from the Miami area and sought Zika testing after becoming ill, the TDSHS said. The department said it would classify the case as “travel-related” and that further investigation is in progress. TDSHS said it linked the case to Miami after closely evaluating travel dates, symptom onset, and known local transmission in Miami. The patient’s illness is El Paso County’s first Zika case, and no evidence of the virus or local transmission has been detected before in the area. So far, Texas has recorded 108 travel-linked Zika cases, 3 of them in pregnant women. However, health officials are on alert for local cases and Texas has taken steps since January to delay and minimize the impact of the virus. Florida’s local infection total climbs to 30 Florida’s governor’s office today said two more local transmissions have been confirmed in Miami-Dade County, raising the number of non-travel related Zika infections in the state to 30. In a statement, Gov Rick types of medical interview Scott said that despite the two additional cases, “We still believe local transmissions are only occurring in an area that is less than 1 square mile in Wynwood.” In a separate statement, the Florida Department of Health (Florida Health) said one of the patients was exposed in the affected Wynwood area and the second was located outside of the 1-square-mile area. So far state health officials are investigating four areas in Miami-Dade and Palm Beach Counties where local Zika transmission may have occurredthree in the former and one in the latter.
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Thanks for taking the questions. ——————————————————————————– Jason Butler, JMP Securities – Analyst  ——————————————————————————– Katie Brennan, Wells Fargo Securities, LLC – Analyst  ——————————————————————————– This is Katie Brennan on for David Maris. Thanks for taking the question. I have a couple. First, on Cotempla XR-ODT’s filing, initially or last quarter, you guys had expected it would be a 3Q filing. And then when you provided the update on the bioequivalence — on the positive bioequivalence outcome, that language changed to by end of year. So can you give us some sense of how certain you are that that filing will happen by year end and what might have caused a slight delay? And then secondly, on the revenue from Adzenys through the rest of the year, can you give us any sort of guidance to help us understand what would be an appropriate benchmark to expect from you guys on that? Thank you.
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